Overview

Clinical Research Fellow – Strand, London, WC2R 2LS

About Us

Based at Guy’s and St Thomas’ Hospitals, our Institute is derived from St John’s Hospital for Diseases of the Skin that was founded in London in 1868.
 
We play a leading role in the training of dermatologists both in the UK and around the world. Our MSc in Clinical Dermatology is world-renowned, and we have an active education programme providing specialist dermatology training.
 
Our research facilities are designed to enable translational human skin research and include cell biology (including cell transfection), immuno-labelling and photomicroscopy, molecular genetic facilities and in vivo sampling techniques (phototesting, skin biopsy and DNA sampling), with appropriate storage techniques.

About the role

Who we are looking for
 
A highly motivated, organised, and collaborative clinician with:
  • Strong interest in clinical trials and translational science
  • Excellent communication, leadership, and problem-solving skills
  • Commitment to rare disease research and patient-centred innovation
  • Ability to operate across clinical, regulatory, and analytical domains
Why this role
This is a rare opportunity to lead a paradigm-shifting clinical trial while undertaking a PhD—gaining deep expertise from trial conception to impact, within a programme designed to accelerate therapies for patients with EB.
 
Learn more about the programme:
 
Base: Guy’s & St Thomas’ Hospitals, London (with flexibility across Trust sites as required by the study)
 
This Clinical Research Fellow post offers a fully funded PhD to lead delivery of a Phase 2/3 multi-arm, multi-stage (MAMS) platform trial evaluating repurposed biologics and biosimilars in adults with epidermolysis bullosa (EB). The programme integrates a parallel non-CTIMP study (MOSAIC) and CTIMP trial (ART-EB Phase 2/3)—the largest and most ambitious drug repurposing effort in EB to date. 
Working under the supervision of Dr Su Lwin (Chief Investigator), you will operate at the interface of clinical trials, immunology, multi-omics and health economics, with direct mentorship from internationally recognised leaders. 
 
This is a full-time post (40 hours per week), and you will be offered a fixed term contract until 30th September 2029.

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