Overview
Bioinformatician – Strand, London, WC2R 2LS
About us
The Department of Medical and Molecular Genetics at King’s College London is at the forefront of human genetics research. We are part of the School of Basic and Medical Biosciences within the Faculty of Life Sciences and Medicine at King’s College London. This post is based in the Department of Medical and Molecular Genetics and supervised by Professor Matthew Brown, working in close collaboration with Professor Emma Duncan of the Department of Twin Research & Genetic Epidemiology. Their collaborative research group focuses on unlocking the genetic basis of common and rare bone and joint diseases, including ankylosing spondylitis and related conditions. We have access to state-of-the-art facilities and are embedded within a global network of collaborators.
About the role
We are seeking a talented and motivated Bioinformatician to join our research group in the Department of Medical and Molecular Genetics at King’s College London. You will play a pivotal role in advancing our understanding of common and rare bone and joint diseases, including the common arthopathy ankylosing spondylitis and related diseases. Supervised by Professor Matthew Brown (Medical and Molecular Genetics) and working closely with Professor Emma Duncan (Twin Research & Genetic Epidemiology), you will harness advanced bioinformatics approaches to decode the genetic underpinnings of these conditions. This will include identification of new disease-associated loci, investigation of functional mechanisms of disease, research into polygenic risk scores (including clinical implementation), and identification of novel therapeutic interventions and personalised treatment strategies. You will collaborate with our global network of researchers and contribute to high-impact publications and grant applications.
Hybrid working is possible, with the postholder expected to work on site approximately 2 days per week.
This is a full-time post and you will be offered a fixed term contract for 1 year.
Research staff at King’s are entitled to at least 10 days per year (pro-rata) for professional development. This entitlement, from the Concordat to Support the Career Development of Researchers, applies to Postdocs, Research Assistants, Research and Teaching Technicians, Teaching Fellows and AEP equivalent up to and including grade 7. Visit the Centre for Research Staff Development for more information.
About you
To be successful in this role, we are looking for candidates to have the following skills and experience:
Essential criteria
- PhD qualified in bioinformatics with a focus on genetic studies of common and/or rare human diseases.
- Proficiency in programming languages used in bioinformatics, such as Python and/or R, with the ability to develop and implement computational solutions for genetic data analysis
- In-depth knowledge and hands-on experience with bioinformatics tools and databases relevant to genetic research, including tools for gene mapping, functional genomics analysis, and polygenic risk score studies
- Excellent written and verbal communication skills, with the ability to convey complex genetic concepts to both technical and non-technical audiences, and a proven ability to contribute to scientific publications
- Ability to adapt to evolving research priorities and methodologies, and demonstrated openness to incorporating new technologies and approaches
- Strong organisational and project management skills, with the ability to plan, execute, and deliver research objectives effectively within specified timelines
Desirable criteria
- Track record of successful collaboration in research projects, ideally in interdisciplinary teams working with researchers, clinicians, and global collaborators
- Experience translating genetic data into actionable insights with potential clinical applications, including understanding the implications of genetic findings for therapeutic development
- Previous experience with laboratory-based functional genomics methodologies, demonstrating practical understanding of integrating wet-lab techniques with computational analyses
Downloading a copy of our Job Description
Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the page. This document will provide information of what criteria will be assessed at each stage of the recruitment process.
IMPORTANT: Before applying for this role, please make sure you have the right to work in the country where the role is based. Unless it clearly stipulates within in the job advert above that the hiring company is looking to or able to sponsor applicants it is deemed that the hiring employer will only consider applications from those able to comply with and work in the country where the role is based.
